N- 乙烯基 -N- 甲基乙酰胺

N-vinyl-N-methyl acetamide （ VMA ）

CAS 号： 3195-78-6
简介
　　VMA 属于氮 - 乙烯基化合物中非常重要的一种。由于羰基及乙烯基连接在同一个氮原子上，使得此类化合物具有良好的聚合特性及高的反应活性，在工业上作为非常重要的活性单体，被广泛用于特种聚合物及紫外光固化树脂。
理化特性
　　外观：无色至浅黄色透明液体
　　分子式： C 5 H 9 NO
　　分子量： 99.15
　　比重： 0.9600 g/cm 3
　　沸点： 163 - 165 ℃ @760 mm Hg
　　熔点： -36 ℃
　　闪点： 60 ℃
　　蒸汽压： 1.8 mbar @ 20 ℃
　　折射率： 1.4830- 1.4850
用途
　　VMA 的均聚物或共聚物可用于水溶性聚合物、隐形眼镜树脂、紫外光固化树脂、高效阳离子絮凝剂、水土保持剂、纺织印染工业中的助剂及污水处理剂等。
潜在健康影响
　　 对眼、皮肤有刺激性，大量吸入其蒸汽会抑制中枢神经系统。
储存
　　 储存于密封容器中，存放于干燥、凉爽、通风良好的地方。远离火源、热源及任何一种引发源。

Material Safety Data Sheet

N-Vinyl-N-methylacetamide, 99%

MSDS Name: N-Vinyl-N-methylacetamide, 99%
Catalog Numbers: AC134122500, AC134125000
Synonyms: Acetamide, N-ethenyl-N-methyl-; N-Ethynyl-N-methylacetamide; N-Methyl-N-vinylacetamide; N-Vinylmethylacetamide

EMERGENCY OVERVIEW

Appearance: clear brown liquid. Flash Point: 60 deg C.
Warning! Causes eye, skin, and respiratory tract irritation. Flammable liquid and vapor. May be harmful if absorbed through the skin. May cause central nervous system depression.
Target Organs: Central nervous system.


Potential Health Effects
Eye: Causes eye irritation.
Skin: Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Ingestion of large amounts may cause CNS depression.
Inhalation: Inhalation at high concentrations may cause CNS depression and asphixiation. Causes irritation of the mucous membrane and upper respiratory tract.
Chronic: No information found.

Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid imme diately.
Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically and supportively.

General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors can travel to a source of ignition and flash back. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Combustible liquid. Vapors may be heavier than air. They can spread along the ground and collect in low or confined areas. Containers may explode when heated. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media: Use water spray to cool fire-exposed containers. Use water spray, dry chemical, carbon dioxide, or appropriate foam.
Flash Point: 60 deg C ( 140.00 deg F)
Autoignition Temperature: 310 deg C ( 590.00 deg F)
Explosion Limits, Lower: Not available.
Upper: Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 2; Instability: 0

General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool.

Handling: Wash thoroughly after handling. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Use and store under nitrogen. Use only in a chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Do not breathe vapor.
Storage: Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Keep containers tightly closed.

Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local explosion-proof ventilation to keep airborne levels to acceptable levels.
Exposure Limits

OSHA Vacated PELs: N-Vinyl-N-methylacetamide: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear chemical splash goggles.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Physical State: Liquid
Appearance: clear brown
Odor: None reported.
pH: Not available.
Vapor Pressure: 1.8 mbar @ 20 deg C
Vapor Density: 3.42
Evaporation Rate: Not available.
Viscosity: 1.28 MPA 20.00 deg
Boiling Point: 165 - 168 deg C @ 760 mm Hg
Freezing/Melting Point: -36 deg C
Decomposition Temperature: Not available.
Solubility: miscible
Specific Gravity/Density: 0.9600g/cm3
Molecular Formula: C5H9NO
Molecular Weight: 99.10

Chemical Stability: Stable under normal temperatures and pressures.
Conditions to Avoid: Ignition sources, excess heat.
Incompatibilities with Other Materials: Strong oxidizing agents, strong acids.
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Has not been reported.

RTECS#:      
CAS# 3195-78-6: AC6475000
LD50/LC50:
CAS# 3195-78-6:
     Oral, rat: LD50 = 2830 uL/kg;
     Skin, rabbit: LD50 = 1410 uL/kg;
.
Inhalation, rat: LC >4000
Carcinogenicity:
CAS# 3195-78-6: Not listed by ACGIH, IARC, NTP, or CA Prop 65.

Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: No information found
Mutagenicity: No information found
Neurotoxicity: No information found
Other Studies:

No information available.

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

US FEDERAL

TSCA
     CAS# 3195-78-6 is listed on the TSCA inventory.
Health & Safety Reporting List
     None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
     None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
     None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
     None of the chemicals in this material have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding RQs
     None of the chemicals in this material have an RQ.
SARA Section 302 Extremely Hazardous Substances
     None of the chemicals in this product have a TPQ.
Section 313      No chemicals are reportable under Section 313.
Clean Air Act:
     This material does not contain any hazardous air pollutants.
     This material does not contain any Class 1 Ozone depletors.
     This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
     None of the chemicals in this product are listed as Hazardous Substances under the CWA.
     None of the chemicals in this product are listed as Priority Pollutants under the CWA.
     None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
     None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
     CAS# 3195-78-6 is not present on state lists from CA, PA, MN, MA, FL, or NJ.

California Prop 65

California No Significant Risk Level: None of the chemicals in this product are listed.

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
     XN
Risk Phrases:
     R 21 Harmful in contact with skin.
     R 36 Irritating to eyes.

Safety Phrases:
     S 20 When using do not eat or drink.
     S 37/39 Wear suitable gloves and eye/face protection.

WGK (Water Danger/Protection)
     CAS# 3195-78-6: 1
Canada - DSL/NDSL
     CAS# 3195-78-6 is listed on Canada's NDSL List.
Canada - WHMIS
     This product has a WHMIS classification of B3, D2B.
This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations.
Canadian Ingredient Disclosure List